USPlabs Jack3d- FORMULA BREAKDOWN

Schizandrol A

This compound is an exciting one...

t has also been shown to greatly increase the capacity of muscles to perform work, while also increasing physical force. In essence, it is able to provide a stimulating effect to the body and mind [1].

Last, but certainly not least; unlike various stimulants which can increase catabolic hormone levels (i.e. glucocorticoids), this compound has been shown to lower levels of hormones like cortisol in animal models [2].

And, as we all know, cortisol can be dramatically increased during a workout and can stop muscle growth in its tracks.

Caffeine

Caffeine belongs to the family of methylxanthine compounds. It's able to stimulate the CNS, while also stimulating contractility of skeletal muscle directly and this may partially be due to the release of catecholamines such as norepinephrine.

Caffeine has the benefit of fighting fatigue and drowsiness; enhancing the flow of thoughts; increasing alertness and improving intellectual efforts along with producing euphoria or a sense of well-being in some cases. [3-6].

In terms of specifics, at the cortical level, caffeine is also thought to promote increased wakefulness or vigilance, via adenosine receptor antagonism, causing stimulation of cholinergic neurons in the basal forebrain and reinforcing inhibition exerted upon sleep-promoting GABA neurons. The stimulant effects are exerted directly upon the cerebral cortex, medulla oblongata, and spinal cord.

...Most formulas just throw in a ton of caffeine and hope for the best.

Jack3d's ingredients are perfectly blended for an awesome synergistic effect...

This is one area where USPlabs Jack3d truly separates itself. It's not just a ton of caffeine thrown in so you can "feel it."

Beta-alanine

Beta-alanine serves as the rate-limiting precursor of carnosine and as such, it has been shown that by supplementing with beta-alanine, you can greatly increase carnosine levels in skeletal muscle tissue.

Carnosine is an extremely important dipeptide that is generally present in rather high concentrations in skeletal muscle, though it is also found in nervous tissue and other excitable tissues as well [12,13].

It is so important because it acts as a buffer of sorts, preventing the increase of acidity or Hydrogen ion accumulation in skeletal muscle; something which is thought to contribute to the fatiguing of muscles.

In short, you are able to delay fatigue; allowing you to lift for longer periods.

It is no coincidence that the most explosive athletes (e.g. sprinters) in the world have higher carnosine levels in their muscles. Looking to the animals of our world provides us with yet another example; the most explosive animals such as greyhounds and thoroughbred horses also have the highest level of carnosine in their muscle tissue as well.
Creatine Monohydrate

While we may negate the increase in Hydrogen ion levels in skeletal muscle by increasing carnosine levels, we still must overcome one more obstacle in order to allow us to prevent fatigue while working out. In this case, we must use a compound which can ultimately increase the adenosine triphosphate (ATP) levels in muscle. ATP, as we all know, is a high energy nucleotide which acts as the major energy carrying molecule in our bodies.

Consequently, muscle fatigue is also related to energy loss in skeletal muscle, specifically, ATP being converted to adenosine diphosphate (ADP). In effect, one phosphate group is lost and must be replenished in order for the muscle cell to continue on working.

By supplementing with creatine, we are able to increase the levels of phosphocreatine in muscle. Phosphocreatine is a high energy buffering compound which is able to donate a phosphate group to ADP, allowing the formation of ATP once again.

In short, we can prevent or reduce fatigue from occurring by increasing phosphocreatine levels, which in turn will allow for the regeneration of ATP from ADP.

By addressing both the regeneration of ATP, while also limiting Hydrogen ion accumulation, we are able to provide a one-two combination that effectively reduces fatigue to an amazing degree.

While creatine monohydrate isn't new or ground-breaking, it's scientifically sound, proven millions of times over in the real-world and an absolute must in any pre-workout formula [8-11]. 

The "Best" Creatine?

It seems there have been a myriad of creatine products on the market in recent years; each and every one of them claim to improve upon the original creatine monohydrate. Yet, not one of them has ever been able to do so. Though, should this really be a surprise?

It has been known for some time now that creatine monohydrate's bioavailability is nearly 100%,despite many marketing attempts to make you believe otherwise.

Yet, each one of these products has claimed that they could improve the product in some way.

The reason for the stomach issues associated with creatine was the loading phase that was promoted when creatine first came out. This has since been disproven & NOT needed to achieve desired results...

First it was the effervescent formulations, claiming that the buffered product could resist acidic degradation of creatine to creatinine in the stomach, while at the same time, decreasing the transit time for the creatine to enter the small intestine from the stomach, again, hypothetically reducing the amount of creatine degradation.

Last, it was supposed to improve solubility of the creatine in solution, hypothetically resulting in improved absorption. Yet, scientific studies showed no improvement in absorption or bioavailability with these formulations.

The next attempt was to improve creatine absorption with various salts, the latest of which appear to be tri-creatine citrate and creatine pyruvate. Yet again, as you would expect, studies have shown no significant increase in bioavailability over regular creatine monohydrate.

Don't be fooled by slick marketing; some manufacturers may cite a study which had shown slightly greater (although not statistically significant and hence not accepted as likely being unique) plasma concentrations of creatine with the pyruvate salt in particular.

However, they will most certainly and conveniently leave out the scientists' own conclusions, "The higher plasma concentration with Creatine Pyruvate is unlikely to have been due to greater bioavailability, since the bioavailability of Creatine Monohydrate is known to be close to 100%" and "It is questionable if the small differences observed in the plasma concentrations with the three treatments would have any effect on the increase in creatine in muscle."

Yet another example of these futile attempts includes the creatine ethyl ester. This particular product also boasted claims of improved bioavailability by preventing the degradation of creatine to creatinine in the stomach, while also improving physiochemical properties conducive of improved bioavailability.

Yet again, the product failed to do so. In fact, not only did the addition of the ethyl ester not help, it actually was shown to accelerate the degradation of creatine to creatinine in an acidic solution. It can be estimated from such studies that the bioavailability of the creatine ethyl ester is actually far less than regular creatine monohydrate, which again, is already nearly 100% to begin with.

Perhaps other manufacturers will finally get the hint that creatine monohydrate isn't going to be improved upon as there is virtually no room for improvement. Yet, that won't stop them as history has shown.

Creatine monohydrate after all is an effective product. In fact, it's probably one of, if not the most scientifically validated dietary supplement in existence and it delivers real world results as well.

But remember, the marketing arm of these companies are banking on the fact that creatine is such a great supplement; a supplement that has become a staple for nearly all athletes and weightlifters, that they want to create their own unique version, touting some supposed added benefits. But as you've learned, there is no such thing.

"Jacob, doesn't creatine need a delivery system?"

Delivery Systems? Delivery Systems? You Talkin' Bout Delivery Systems?

The lack of bio-availability is NOT what causes the side effects from creatine.

It's the "loading phase" (20-30 grams per day!) that was initially touted (and still used by some today) when creatine first hit the shelves in the 90's...

Absolutely "genius" in marketing, as the "loading phase" quadrupled initial sales and caused an almost instant water weight gain so users were thrilled...

However, it wasn't all sunshine...

Peak creatine concentration in the body has a ceiling. Meaning, when peak concentration is reached, the body has no more room for the extra creatine...

So, it "flushes" it out...And this is why creatine got a bad rap for not "absorbing" when, in essence, it was poor application...

You only need a few grams of creatine per day, that's it...

After 7-14 days, whether you take 30 grams of creatine a day or 2 grams of creatine a day, your blood concentration levels of creatine will be exactly the same...

Geranium (1,3-Dimethylamylamine)

Geranium has a long history of being used for many purposes in the food supply. It contains a constituent that may provide a boost to your workouts & help you power through tough set after tough set - always ready to take on the next challenge.

L-arginine alpha-ketoglutarate (AAKG)

This particular compound was included in the formula as it may also increase strength and peak power performance.

Yet as an added benefit, by including a very precise amount, in combination with other ingredients, one can also experience an increase in vasodilation, which can potentially increase the flow of nutrients to skeletal muscle.

In addition, this vasodilation may result in increased glycogen storage, which in turn may increase cellular swelling of skeletal muscle [14]. Based on animal models, this cellular swelling is hypothetically capable of producing anabolic effects in skeletal muscle, while at the same time, producing an increased "pumped" sensation in muscle, making your workouts all the more pleasing.

ULTRA-CONCENTRATED QUALITY

You may have noticed the ultra-concentration trend over the last few years that virtually everymajor corporation has used to conserve energy, reduce waste and lower costs. 
From cars to food to even household items like dish detergent...

With the way our environment & economy is, we simply cannot afford any waste whatsoever. The price is just too high. The supplement industry is no different...

As mentioned above, USPlabs Jack3d contains as many servings, and is more potent, than products three or four times its size. I mean, who the heck wants to pay for unnecessary fillers?

USPlabs Jack3d is ultra-concentrated with only the highest quality ingredients available.

How Does It Taste?

In a word...AMAZING!

Sure, you'll hear that from most companies, yet virtually all of the pre-workout drinks on the market are, at best, tolerable.

And, let's be honest, most taste like crap...

...In addition, most drinks require 16-20oz of water (hey, all those fillers have to dissolve somehow!), leaving you bloated & sluggish...NOT the best environment for attacking the weights.

USPlabs Jack3d requires only 4-8oz and is probably the best tasting pre-workout drink... ever!

With pleasant Tropical Fruit Punch , Lemon-Lime & Grape Bubblegum flavors that goes down smooth and refreshing, you'll be shocked it's as good as it is - it's simply a joy to drink!